Product Description

Dosage form and Strength of Sigrima 420mg/14ml (Pertuzumab) Injection:
It is in Injection form.
Each ml of the solution contains Pertuzumab 30mg.

Mechanism of Action of Sigrima 420mg/14ml (Pertuzumab) Injection:
It inhibits the dimerization of HER2 with other HER receptors, which prevents them from signalling in ways that promote cell growth and proliferation.

Administration of Sigrima 420mg/14ml (Pertuzumab) Injection:
It is a concentrate for solution for Intravenous Infusion.
Must dilute prior to use.
Single dose vial.
Do not self-medicate the therapy.
Use it under a medical supervision only.

Therapeutic Use of Sigrima 420mg/14ml (Pertuzumab) Injection:
It is an anticancer medication.
It is used to treat certain types of breast cancer.
It is also used to treat early-stage breast cancer in patients who will be having surgery to remove the cancer.

Usage Instruction of Sigrima 420mg/14ml (Pertuzumab) Injection:
For Intravenous Infusion after dilution.
Single use vial.
Do not self-medicate the therapy.
Take the dosage as directed by the Oncologist.
Keep out of reach of children.

Side Effects:
Diarrhoea,
Nausea,
Heartburn,
Hair loss,
Muscle pain,
Cough,
Tiredness,
Decreased blood cells,
Stomach inflammation,
Fatigue.

Safety Precautions:

Alcohol:
The study of the Injection in alcoholic patient is not known.
However, it is advisable to consult a doctor for personalized advice.

Pregnancy:
It is unsafe to use during pregnancy.
It may harm an unborn baby.
Pregnant women should consult their doctor for alternative treatment options.

Lactating Mothers:
It is also unsafe to use while breastfeeding.
Lactating mothers should seek medical advice for appropriate alternatives.

Driving:
It is not known whether it may affect the ability to drive, as only limited information is available.
However, it is important to consult a doctor for guidance on driving safety.

Renal Impairment:
It is generally safe to be used in patients with Renal Impairment.
However, it is important to consult a doctor for proper evaluation and potential dosage adjustments.

Hepatic Impairment:
The study of the Injection in Hepatically Impaired patients is not known, as there are only limited information available.
Consulting a doctor is crucial for appropriate guidance.

Contraindications:
Known hypersensitivity.

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