Product Description

Dosage form and Strength of Palbocib 125mg (Palbociclib) Capsules:
It is a hard gelatin Capsules.
Each hard gelatin Capsules contains Palbociclib 125mg.

Mechanism Of Action of Palbocib 125mg (Palbociclib) Capsules:
It is a selective inhibitor of cyclin-dependent kinase (CDK) 4 & 6.
Through inhibition of cyclin D- CDK 4/6 complex activity it inhibits the phosphorylation of retinoblastoma (Rb) protein thus blocking cycle progression.
It also targets the estrogen receptor positive breast cancer cells by disrupting the cell cycle.
It aims to slow or stop the growth of the cancer.

Administration of Palbocib 125mg (Palbociclib) Capsules:
It is to be used orally.
It is to be taken with food.
Do not self-medicate the therapy.
Take the dosage as prescribed by the doctor.

Therapeutic Use of Palbocib 125mg (Palbociclib) Capsules:
It is used in the treatment of Breast Cancer.
It is also to tear Hormone Receptor (HR)- positive, Human Epidermal Growth Factor Receptor 2 (HER2)- negative metastatic breast cancer.

Usage Instruction of Palbocib 125mg (Palbociclib) Capsules:
For oral use only.
It is to be taken orally with Food.
Do not self-medicate the therapy.
Take the dosage as prescribed by the doctor.

Side Effects:
Decreased blood cells and platelets,
Anaemia,
Diarrhoea,
Fever,
Hair loss,
Skin rash,
Loss of appetite,
Fatigue,
Dizziness,
Infections,
Sores on the lips, mouth or throat,
Changes in the taste,
Tiredness,
Numbness or tingling in the hands, feet or leg.

Safety Precautions:

Alcohol:
The study of the capsule in alcoholic patient is not known.
However, it is advisable to consult a doctor for personalized advice.

Pregnancy:
It is unsafe to use during pregnancy.
It may harm an unborn baby.
Pregnant women should consult their doctor for alternative treatment options.

Lactating Mothers:
It is also unsafe to use while breastfeeding.
Lactating mothers should seek medical advice for appropriate alternatives.

Driving:
It may affect the ability to drive, so it is recommended to avoid driving after taking the medication.
Consult your doctor for guidance on driving safety.

Renal Impairment:
It is generally safe to use in patients with Renal Impairment.
Precaution should be taken while using this medication.
However, it is important to consult a doctor for proper evaluation and potential dosage adjustments.

Hepatic Impairment:
Precaution should be taken when using the capsule in patients with Hepatic Impairment.
Consulting a doctor is crucial for appropriate guidance.

Contraindications:
Known hypersensitivity.
Known or Suspected Pregnancy.

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