Product Description

Dosage form and Strength of Entresto 100mg (Sacubitril 49mg + Valsartan 51mg) Tablet:
It is a film-coated tablet.
Each film-coated tablet contains Sacubitril and Valsartan 100mg (49mg + 51mg).

Mechanism Of Action of Entresto 100mg (Sacubitril 49mg + Valsartan 51mg) Tablet:
It is a combination of two drugs.
Sacubitril and Valsartan exhibits mechanism of action of an angiotensin receptor neprilysin inhibitor (ARNI) by simultaneously inhibiting neprilysin.
Sacubitril lowers blood pressure by causing blood vessel relaxation, excretion of sodium through urine and increasing urination. Valsartan works by relaxation of blood vessels so that the heart pumps blood more easily through blood vessels to the body.
This helps to relax the blood vessel and makes heart easy to pump blood flow throughout the body.

Administration of Entresto 100mg (Sacubitril 49mg + Valsartan 51mg) Tablet:
It is to be used orally.
Do not self-medicate the therapy.
Take the medicine as directed by the physician.

Therapeutic Use of Entresto 100mg (Sacubitril 49mg + Valsartan 51mg) Tablet:
It is used in the treatment of Heart Failure by relaxing the blood vessels and making it easier for your heart to pump blood throughout your body.
It helps to treat long term Heart failure.
It reduces the risk of Cardiovascular complications and reduce ejection fraction.

Usage Instruction of Entresto 100mg (Sacubitril 49mg + Valsartan 51mg) Tablet:
For oral use only.
Do not self-medicate the therapy.
Take the medicine as directed by the physician.
Keep out of reach of children.

Side Effects of Entresto 100mg (Sacubitril 49mg + Valsartan 51mg) Tablet:
Dizziness,
Stomach pain,
Nausea,
Vomiting,
Diarrhoea,
Cough,
Decreased blood pressure,
Headache,
Fainting,
Irregular heartbeat,
Weakness,
Flushing,
Edema.

Safety Precautions:

Alcohol:
It is generally unsafe to be used in alcoholic patients.
However, it is advisable to consult a doctor for personalized advice.

Pregnancy:
It is unsafe to use during pregnancy.
It may harm an unborn baby.
Pregnant women should consult their doctor for alternative treatment options.

Lactating Mothers:
It is to be used with precaution while breastfeeding.
Lactating mothers should seek medical advice for appropriate alternatives.

Driving:
It may affect the ability to drive, so it is recommended to avoid driving after taking the medication.
Consult your doctor for guidance on driving safety.

Renal Impairment:
It should be used cautiously in Renally Impaired patients.
However, it is important to consult a doctor for proper evaluation and potential dosage adjustments.

Hepatic Impairment:
It should be used cautiously in Hepatically Impaired patients.
Consulting a doctor is crucial for appropriate guidance.

Contraindications:
Known hypersensitivity.
Angioedema.
ACE Inhibitors.

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