Product Description

Dosage form and Strength of Arranon 250mg (Nelarabine) Injection:
It is supplied as a clear, colorless sterile solution for injection.
Each vial contains Nelarabine 250mg/50ml i.e. (5mg/ml) single dose vial.

Mechanism Of Action of Arranon 250mg (Nelarabine) Injection:
It is from a group of drugs known as antimetabolites.
It involves the transformation of the pro-drug into the deoxyguanosine analogue 9-β-D-arabinofuranosylguanine (ara-G).
Nelarabine is a prodrug of the deoxyguanosine analogue 9-β-D-arabinofuranosylguanine (ara-G), a nucleoside metabolic inhibitor.

Administration of Arranon 250mg (Nelarabine) Injection:
It is to be used as Intravenous Infusion.
Do not self-medicate the therapy.
Use it under a medical supervision only.

Therapeutic Use of Arranon 250mg (Nelarabine) Injection:
It is used in the treatment of T- cell acute lymphoblastic leukemia (T-ALL) and T- cell lymphoblastic lymphoma (T-LBL).

Usage Instruction of Arranon 250mg (Nelarabine) Injection:
It is to be used as Intravenous Infusion.
Single use vial.
Do not use if the solution is cloudy or contains a precipitate.
Discard unused portion.
Do not self-medicate the therapy.
Use it under a medical supervision only.

Side Effects:
Nausea,
Vomiting,
Constipation,
Headache,
Cough,
Diarrhoea,
Dizziness,
Drowsiness,
Tiredness,
Loss of appetite.

Safety Precautions:

Alcohol:
The study of the Injection in alcoholic patient is not known.
However, it is advisable to consult a doctor for personalized advice.

Pregnancy:
It is unsafe to use during pregnancy.
Precaution is necessary when using this medication.
It may harm an unborn baby.
Pregnant women should consult their doctor for alternative treatment options.

Lactating Mothers:
The study of the Injection in Lactating Mothers is not known.
Precaution is necessary when using this medication.
Lactating mothers should seek medical advice for appropriate alternatives.

Driving:
It may affect the ability to drive, so it is recommended to avoid driving after taking the medication.
Consult your doctor for guidance on driving safety.

Renal Impairment:
It should be used with caution in Renally Impaired Patient.
However, it is important to consult a doctor for proper evaluation and potential dosage adjustments.

Hepatic Impairment:
It should be used with caution in Hepatically Impaired Patient.
Consulting a doctor is crucial for appropriate guidance.

Contraindications:
Known hypersensitivity.

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