Product Description

Dosage form and Strength of Apristar 125mg/80mg (Aprepitant) Capsule:
It is a hard gelatin capsule.
Each hard gelatin capsule kit contains Aprepitant IP 125mg and Aprepitant IP 80mg.

Mechanism of Action of Apristar 125mg/80mg (Aprepitant) Capsule:
It is a NK1 antagonist, as it block’s signals given by NK1(Neurokinin) receptors.
It inhibits both the acute and delayed emesis induced by cytotoxic chemotherapeutic drugs by blocking P landing on receptors in the brain’s neurons.
It works by blocking the transmission of nerve signals between the vomiting centres and the brain.

Administration of Apristar 125mg/80mg (Aprepitant) Capsule:
It is to be taken orally with or without food.
Do not self-medicate the therapy.
Take the dosage as directed by the physician.

Therapeutic Use of Apristar 125mg/80mg (Aprepitant) Capsule:
It is an antiemetic medicine.
It is used to prevent chemotherapy induced Nausea and Vomiting.
It is also used in the prevention of postoperative Nausea and Vomiting in adults.

Usage Instruction of Apristar 125mg/80mg (Aprepitant) Capsule:
For Oral use only.
Do not self-medicate the therapy.
Take the dosage as directed by the physician.
Keep out of reach of children.

Side Effects:
Headache,
Hiccups,
Loss of appetite,
Constipation,
Fatigue,
Increased liver enzyme,
Tiredness,
Indigestion,
Diarrhoea,
Dizziness.

Safety Precautions:

Alcohol:
The study of the capsule in alcoholic patients is not known.
However, it is advisable to consult a doctor for personalized advice.

Pregnancy:
The study of the capsule in Pregnant women is not known.
Pregnant women should consult their doctor for alternative treatment.

Lactating Mothers:
It is unsafe to use while breastfeeding.
Lactating mothers should seek medical advice for appropriate alternatives.

Driving:
It may affect the ability to drive, so it is recommended to avoid driving after taking the medication.
Consult your doctor for guidance on driving safety.

Renal Impairment:
It is generally safe to use in patients with Renal Impairment.
However, it is important to consult a doctor for proper evaluation and potential dosage adjustments.

Hepatic Impairment:
It is generally safe to use in patients with Hepatic Impairment.
However, it is important to consult a doctor for proper evaluation and potential dosage adjustments.

Contraindications:
Known hypersensitivity.

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