Product Description

Dosage form and Strength of Apriset 150mg (Fosaprepitant Dimeglumine) Injection:
It is a Lyophilized Injection.
Each vial contains Fosaprepitant Dimeglumine 245.3mg, equivalent to Fosaprepitant 150mg.

Mechanism Of Action of Apriset 150mg (Fosaprepitant Dimeglumine) Injection:
It is a NK1 antagonist, as it blocks signals given by NK1(Neurokinin) receptors.
It inhibits both the acute and delayed emesis induced by cytotoxic chemotherapeutic drugs by blocking P landing on receptors in the brain’s neurons.
It works by blocking the transmission of nerve signals between the vomiting centres and the brain.

Administration of Apriset 150mg (Fosaprepitant Dimeglumine) Injection:
It is to be used as Intravenous Injection one hour before the chemotherapy session.
Single dose vial.
Discard unused portion.
Do not self-medicate the therapy.
Use it under a medical supervision only.

Therapeutic Use of Apriset 150mg (Fosaprepitant Dimeglumine) Injection:
It is an antiemetic medicine.
It is used to prevent chemotherapy induced Nausea and Vomiting.
It is also used in the prevention of postoperative Nausea and Vomiting in adults.

Usage Instruction of Apriset 150mg (Fosaprepitant Dimeglumine) Injection:
For Intravenous Infusion, use only after reconstitution and dilution.
Single dose vial.
Discard unused portion.
Do not self-medicate the therapy.
Use it under a medical supervision only.

Side Effects:
Headache,
Hiccups,
Loss of appetite,
Constipation,
Fatigue,
Increased liver enzyme,
Tiredness,
Indigestion,
Diarrhoea,
Dizziness.

Safety Precautions:

Alcohol:
It is generally considered safe to use in alcoholic patients.
However, it is advisable to consult a doctor for personalized advice.

Pregnancy:
It is unsafe to use during pregnancy.
It may harm an unborn baby.
Pregnant women should consult their doctor for alternative treatment options.

Lactating Mothers:
It is also unsafe to use while breastfeeding.
Lactating mothers should seek medical advice for appropriate alternatives.

Driving:
It may affect the ability to drive, so it is recommended to avoid driving after taking the medication.
Consult your doctor for guidance on driving safety.

Renal Impairment:
It is generally safe to use in patients with Renal Impairment.
However, it is important to consult a doctor for proper evaluation and potential dosage adjustments.

Hepatic Impairment:
It is generally safe to use in patients with Hepatic Impairment.
However, it is important to consult a doctor for proper evaluation and potential dosage adjustments.

Contraindications:
Known hypersensitivity.
Known or suspected pregnancy.

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